Title:
Compuestos bioactivos y propiedades terapéuticas de los cálices de rosa de Jamaica (Hibiscus Sabdariffa Linn). --
Varying form of title:
Bioactive compounds and therapeutic properties of Jamaica rose calyxes (Hibiscus sabdariffa Linn.). --
Classification:
RCQF20142401a
Summary:
El potencial farmacológico de los extractos del cáliz de Hibiscus sabdariffa L. en alteraciones metabólicas como hipertensión, dislipidemia e hiperuricemia, ha sido demostrado in vitro, in vivo y en ensayos clínicos, observándose una estrecha relación con la estabilidad química en la extracción y almacenaje de los compuestos bioactivos, así como en su comportamiento en los compartimientos biológicos. En vista de sus propiedades farmacológicas y su alta seguridad reportada, los extractos y sus compuestos aislados podrían ser fuente de productos terapéuticamente útiles. El objetivo de ésta revisión es examinar la evidencia de los compuestos bioactivos, los factores que influyen en su potencial farmacológico y la efectividad y seguridad terapéutica de H. sabdariffa demostrada a nivel in vivo y en ensayos clínicos. --
ABSTRACT: The pharmacological potential of Hibiscus sabdariffa L. calyxes extracts in metabolic desorders such as hypertension, dyslipidemia and hyperuricemia has been demonstrated in vitro, in vivo and clinical trials, showing a close relationship with the chemical stability, in the extraction and storage of bioactive compounds and their behavior in biological compartments. In view of its pharmacological properties and its high security reported, extracts and isolated compounds (anthocyanins and protocatechuic acid) could be a source of therapeutically useful products. The aim of this review is to examine the evidence of bioactive compounds, the factors that influence their pharmacological potential and therapeutic effectiveness and safety of H. sabdariffa demonstrated in vivo and in clinical trials. --
ABSTRACT: The pharmacological potential of Hibiscus sabdariffa L. calyxes extracts in metabolic desorders such as hypertension, dyslipidemia and hyperuricemia has been demonstrated in vitro, in vivo and clinical trials, showing a close relationship with the chemical stability, in the extraction and storage of bioactive compounds and their behavior in biological compartments. In view of its pharmacological properties and its high security reported, extracts and isolated compounds (anthocyanins and protocatechuic acid) could be a source of therapeutically useful products. The aim of this review is to examine the evidence of bioactive compounds, the factors that influence their pharmacological potential and therapeutic effectiveness and safety of H. sabdariffa demonstrated in vivo and in clinical trials. --
Original document:
En: Revista Científica de la Facultad de Ciencias Químicas y Farmacia y del Instituto de Investigaciones Químicas y Biológicas de la USAC ; (Vol.24 No.1) p.07-24. -- Guatemala : USAC, 2014. 2070-8246.
Locations & copies:
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